Monthly Archives: June 2011

In case you’ve just missed it…

Fixing the Brain-Computer Interface

Researchers are addressing the sizable population for whom
BCI doesn’t work

By Erica
Westly  /  June 2011


New website (in Dutch): http://www.braininnovations.nl/

It takes some cooking to prepare a good meal

Frequent readers of this weblog may have started to wonder whether the activities of the Biomedical Electronics Group have gradually fainted and dissolved in eternity, its members have all become hobos and it all ended in a big dream. Bzinga. The truth is, of course, that everybody is very busy and under the yoke of some deadline or another.

Senad and June been working very hard on a first proof-of-principle of a Tinnitus detector circuit. Such a circuit should allow for detection of the spatial properties of tinnitus and give objective information on its severity. This could, in turn, lead to more refined or adjusted stimulation therapies. Don’t sell your mother for it, yet, but expectations are high. The findings will be worked out in a manuscript, to be submitted to the annual BioCAS Conference today.

On the detection side of things, Yongjia has been working very hard on the new type of level-crossing analog-to-digital converter, described in an earlier weblog. Also this work will be submitted to the BioCAS Conference.

Duan Zhao received the good news that our paper (together with the Holst Centre) on a reconfigurable subsampling receiver has been accepted for presentation and publication at the PIMRC Conference in Toronto. Congratulations. He just returned from a visit to his home country and we’re happy to have him back again.

Of course there is more that can be reported, such as the coming ELCA day trip, the preparations for organizing BioCAS 2013 in Delft, the IMDI NeuroControl, more power-efficient neurostimulation circuits, higher-efficiency RF energy harvesting circuits, June’s paper that got accepted in Transactions on Circuits and Systems-I: Regular Papers (congrats, too), Sandro’s and Senad’s paper that enjoyed the same fate (congrats, too), STW Perspectief and how the Dutch Ministries of Economical Affairs, Agriculture and Innovation and of Health, Wellbeing and Sport have no clue on how to increase valorization in the Netherlands (as witnessed yesterday at the MedTech West Event), but this would make good stuff for another blog. So stay tuned!

Wouter

Mr. Brain: The Role of Neuroscience in Crime Investigation

More than a week ago, Wouter recommended a Dutch documentary ‘Mystery of the brain’. I believe that the documentary must be very interesting but unfortunately I don’t understand Dutch… What a pity.

I also would like to share my experience with you all in a way that is more relaxing. There is a Japanese TV series called “Mr. Brain” that we can watch online at http://www.youtube.com/watch?v=pKjHIIK7qew&feature=related.

After being busy with my research, watching it reminds me of myself and my work. It makes me smile sometimes. In these series, we will see how the detective and the neuroscientist deal with each other in a bitter-sweet-funny way. Understanding the brain helps a lot in interpreting the evidences that are left behind at the crime scene. Whenever the story goes to a complicated theory of neural processing there will be animations popping up to explain in a very cute way.

It is also good for kids, I think.

A few useful things I got from watching it:

  • I enjoy eating bananas more
  • I know where to sit in front of the girl I meet for the first time
  • Color comes first, shape follows but sound is the most powerful
  • We are using only 5% of our brain. There are still more than enough resources in our brain
  • For creativity, just don’t give up

Like Neil Yongjia said before singing: “I hope you’ll enjoy.”

June

Smaller can be better

After the 2011 edition of ELCA Music Festival, I was dragged (by some mysterious power) deep into the idea that came to my mind around three years ago. At that time, I was trying to simultaneously linearize and reduce a transconductance of a Gm cell (VI converter circuit) for very low frequency biomedical filtering. The linearization and transconductance reduction were successful but the success came prices that I needed to pay:

  1. circuit complexity which is really unfriendly to weak inversion CMOS.
  2. more current consumption which was not surprising. It was very well in line with the circuit complexity. 
  3. more noise contribution (this was also a good friend with circuit complexity).

When I looked into the dynamic range of my design, it was not improved that much from that of an ordinary differential pair circuit (even so the paper was published [1] :). Then I got an idea that ‘instead of inventing a sophisticated linearization technique to obtain larger dynamic range, trying to use as less as possible noisy circuit elements and forget about linearization are more reasonable for biomedical signal processing which requires a good deal of power reduction’. The idea was left there since then for two reasons: I had other jobs to do and the idea seemed too sloppy.

Let me tell you more about the mysterious power. Several times we did rehearsals before the ELCA festival. I was in charge of acoustic guitar and harmonica for the song called ‘The end of the world’ http://www.youtube.com/watch?v=KmnKCE99sYE. Playing two instruments at the same time made me tired and it did not make a good harmony as expected. So I stopped playing the guitar and exercised only the harmonica (of course combined with the piano from Wouter, the electric guitar of Mark and Wannaya’s voice (I could not find this song on our Youtube channel — don’t know why). The song turned out better than before and this reminded me of that sloppy idea!!!

I did an investigation and found that there are strong evidences supporting my idea founded in low-pass filter design [2] [3]… It works!!! Large dynamic range was achieved as well as a very good figure of merit. Although the above filters were dedicated to communication systems rather than for low frequency biomedical signals, the underlying concept of the filter should be applicable for biomedical signal as well. Only a bit more effort was needed to work it out.

Good news!!! Recently, with the help from Senad, who has become 22 years old today — the same as me :). Happy Birthday!!!— my sloppy idea was realized. A 6th-order ECG low-pass filter with a large dynamic range of 59dB and extremely low power consumption of 0.45nW has been designed. We plan to submit this work to BioCAS2011. Hopefully, the reviewers will like it, too.

More good news!!! The application is not limited to low-pass filters only. I’m developing this idea further to apply it for a cochlear channel band-pass filter. What I can say now from the circuit simulations is that the filter provides the best figure of merit compared to state of the art designs. The secret is that all terminals of a single MOSFET device are being used, one pole and one zero are achieved by only two transistors sharing the same bias current.

Next time, I will tell you more about this. Stay tuned if you are interested!!!

Healthy Haring is coming. I heard from Marijn that this year, since the weather is warm, the fish is growing bigger. See you in the Pub this coming Thursday for Harings and Beers 😀

June

[1] C. Sawigun, D. Pal and A. Demosthenous, “A wide linear range transconductor subthreshold transconductor for sub-Hz filtering,” Proc. IEEE ISCAS, pp.1567-1570, 2010

[2] D. Python, A. S. Porret and C. Enz, “A 1V 5th-order Bessel filter dedicated to digital standard proceses,” Proc. IEEE CICC, pp. 505-508, 1999

[3] S. D’Amico, M. Conta and A. Baschirotto, “A 4.1mW 10MHz fourth-order source-follower-based continuous-time filter with 79-dB DR,” IEEE J. Solid-State Circuits, pp. 2713-2719, Dec. 2006