Monthly Archives: September 2011

Wilson Greatbatch, co-inventor of the pacemaker, has died at the age of 92

Wilson Greatbatch

Tuesday 27th of September, the co-inventor of the pacemaker, Wilson Greatbatch, died at the respectable age of 92 years. With the invention of the pacemaker as first implantable medical device, he created the basis of modern implantable medical devices used today. He is also founder of the Greatbatch company which put a lot of effort into the improvement of battery lifetime for implants. I believe that for many of the modern engineers he has been a great and inspiring person.

Cees-Jeroen

Our neurostimulator slowly goes international

http://bulletin.sciencebusiness.net/news/75449/TU-Delft-develops-neurostimulator-to-reduce-Parkinson%E2%80%99s-disease-and-epilepsy-symptoms

http://www.hearing-aid-news.com/tu-delft-develops-neurostimulator-to-reduce-parkinsons-disease-and-epilepsy/

http://www.cattlenetwork.com/cattle-news/Commentary-A-techies-talking-points-130559083.html?ref=083 

http://www.hearingaidtest.com/2011/09/tu-delft-develops-neurostimulator-to-reduce-parkinson%e2%80%99s-disease-and-epilepsy-%e2%80%a6/

http://health.einnews.com/news.php?wid=375454284

http://www.domain-b.com/technology/Health_Medicine/20110927_parkinson.html

http://audiology.advanceweb.com/News/News-Watch/TU-Delft-Attempts-to-Treat-Parkinsons-Epilepsy-and-Tinnitus-with-Neurostimulator.aspx

http://www.aesnet.org/go/news-archive?enddate=09%2F28%2F2011&startdate=09%2F27%2F2011

http://americantinnitusassociation.tumblr.com/post/11285049591/tu-delft-develops-neurostimulator-to-reduce-parkinsons

http://www.tinnitus8.com/domain-b-com-combatting-parkinsons-disease-and-epilepsy-with-neurostimulator.html

http://www.epilepsyresearch.org.uk/news/article.php?id=413

http://foundnewsthatmatters.wordpress.com/epilepsy-news/

Crosslinking the brain

Our work on neurostimulator circuits in the news:

Link 1: http://www.hersenenencognitie.nl/page/1/contents/1323

Link 2: http://drimble.nl/weblogs/onderwijs/universiteit/5921605/tu-delft-gaat-parkinson-en-epilepsie-te-lijf-met-neurostimulator.html

Link 3: http://www.itsallaboutbeauty.nl/?p=3325

Link 4: http://www.blikopnieuws.nl/foto/134767

Link 5: http://www.wetenschap24.nl/nieuws/kort/2011/september/23-september-2011.html

Link 6: http://www.delftnieuws.nl/?item=137982

Link 7: https://www.mijnzorgnet.nl/parkinson/f/122/t/4232.aspx

Link 8: http://www.medicalfacts.nl/2011/09/23/tu-delft-gaat-parkinson-en-epilepsie-te-lijf-met-neurostimulator/

Link 9: http://www.bogobogo.nl/gezondheid/medical-facts/tu-delft-gaat-parkinson-en-epilepsie-te-lijf-met-neurostimulator/

Link 10: http://www.engineersonline.nl/nieuws/id18607-tu-delft-gaat-parkinson-en-epilepsie-te-lijf-met-neurostimulator.html

Link 11: http://www.nationalezorggids.nl/anp/index.php?item_id=315&anp_id=5033

Link 12: http://www.zorginformatiegids.nl/index.php?pagina=nieuws&item=315&anp_id=5033

Link 13: http://www.delta.tudelft.nl/artikel/hersenen-onder-controle/23790

Found via: http://www.google.nl/search?q=neurostimulator+delft

TU Delft to combat Parkinson’s disease and epilepsy with neurostimulator

23 September 2011 by Webredactie

In the future people with brain disorders such as Parkinson’s disease, epilepsy and tinnitus (ringing in the ears) may be fitted with a smart, miniaturised neurostimulator. This stimulator, a prototype of which was recently developed and tested by TU Delft, may considerably reduce the symptoms for some patients. An article on this can be read in the latest edition of Delft Outlook, the TU Delft science magazine, published online today.

Mobile phone

‘A great deal of how we function is determined by electrical currents in our body’, says electrical engineer Marijn van Dongen of TU Delft. ‘We can use this to tackle a whole host of disorders, such as Parkinson’s disease, tinnitus and epilepsy, at a local level. Yet at the same time, this technology is still somewhat “medieval”. At present the neurostimulator is a device the size of a mobile phone which is implanted in the chest. It sends electric pulses via a cable to electrodes in the areas of the brain which show abnormal activity. The electric cables which run through the neck to the brain can break and cause infections. They also lead to the formation of scar tissue in the neck.

SINs

The current design of the neurostimulator is not conducive to further miniaturisation. In order to obviate the need for cables, a complete rethink of the design is needed. Van Dongen is working on this with a large number of colleagues from various knowledge institutes and hospitals, as part of the Smart Implantable Neurostimulators (SINs) programme that started in 2008. In that year, brain surgeons Dirk de Ridder and Eddy van der Velden of Antwerp University Hospital (UZA) contacted electrical engineer Wouter Serdijn of TU Delft. Serdijn is the SINs programme leader. They aim to have developed a cranial-implantable neurostimulator within the next ten years: a two-millimetre thick device measuring two square centimetres including the battery and antenna.

More natural
Challenges facing the researchers in reaching this goal include integrating all the separate components in a single chip, and doing away with the space-consuming capacitors. ‘The stimulators also need to be able to automatically detect when they need to generate pulses, by analysing signals in the brain, just as a pacemaker does in the heart’, says Serdijn. ‘Furthermore, the pattern of the pulses needs to be adjustable and have a more natural form.

Prototype

The TU Delft researchers have already developed and recently tested a prototype. ‘This was a preliminary test to see if our neurostimulator was in fact capable of generating a suitable neural response’, says Van Dongen. It turned out that it was, and the prototype will be further miniaturised in the coming years.For this study Dirk de Ridder and Eddy van der Velden tested the device on themselves: they had temporary electrodes implanted in their body and were able to control the stimulator via an iPhone app.

More information

The latest edition of Delft Outlook, TU Delft’s science magazine, to be published online on 23 September and in print on 26 September, will feature an extensive article on the research conducted by Marijn van Dongen and Wouter Serdijn.

Contact information

Marijn van Dongen (researcher), M.N.vanDongen@remove-this.tudelft.nl tel +31 (0)15-2783679
Dr Wouter Serdijn (SINs programme leader), W.A.Serdijn@remove-this.tudelft.nl tel +31 (0)15-2781715
Nienke van Bemmel (science information officer), n.vanbemmel@remove-this.tudelft.nl +31 (0)15-2784259

Links:
http://www.delftintegraal.tudelft.nl
http://www.braininnovations.nl

Electrical Stimulation of Brain Boosts Birth of New Cells

ScienceDaily (Sep. 22, 2011) — Stimulating a
specific region of the brain leads to the production of new brain cells that
enhance memory, according to an animal study in the September 21 issue of
The Journal of Neuroscience. The findings show how deep brain
stimulation (DBS) — a clinical intervention that delivers electrical pulses to
targeted areas of the brain — may work to improve cognition. Read more.

Hot Wavelets

The paper "Emerging Applications of Wavelet: a review", by Akansu, Serdijn and Selesnick has been declared the hottest (No. 1) paper in Computer Science, Physical Communication (Elsevier) over the period from October 2009 to September 2010. Over the past 9 months, the paper held its No. 1 position firmly, so it is thus heading for becoming the hottest paper for two consecutive years!

ELCA Festival, 2012 Edition will be on Friday, January 13

PSSST! Mark your calendar!

I’m back!

After one year of absence since I graduated for my master thesis, I can happily tell you that I’ m back :). On September 1 I started my PhD research on neural readout circuitry in cochlear implants.

The project is a collaboration between Delft University of Technology and Leiden University Medical Center and is funded by STW (Dutch Technology Foundation). It is called ReaSONS (Realtime Sensing of Neural Signals). Within this project we aim to develop new technology to record the evoked Compound Action Potential (eCAP) generated by the hair cells in the cochlea.

As soon as I have my first results I will let you know. Stay tuned!

Cees-Jeroen