Author Archives: Wouter Serdijn

Does enriched acoustic environment in humans abolish chronic tinnitus clinically and electrophysiologically?

Animal research has shown that loss of normal acoustic stimulation can increase spontaneous firing in the central auditory system and induce cortical map plasticity. Enriched acoustic environment after noise trauma prevents map plasticity and abolishes neural signs of tinnitus. In humans, the tinnitus spectrum overlaps with the area of hearing loss. Based on these findings it can be hypothesized that stimulating the auditory system by presenting music compensating specifically for the hearing loss might also suppress chronic tinnitus. To verify this hypothesis, a study was conducted in three groups of tinnitus patients. One group listened just to unmodified music (i.e. active control group), one group listened to music spectrally tailored to compensate for their hearing loss, and a third group received music tailored to overcompensate for their hearing loss, associated with one (in presbycusis) or two notches (in audiometric dip) at the edge of hearing loss. Our data indicate that applying overcompensation to the hearing loss worsens the patients’ tinnitus loudness, the tinnitus annoyance and their depressive feelings.
No significant effects were obtained for the control group or for the compensation group. These clinical findings were associated with an increase in current density within the left dorsal anterior cingulate cortex in the alpha2 frequency band and within the left pregenual anterior cingulate cortex in beta1 and beta2 frequency band. In addition, a region of interest analysis also demonstrated an associated increase in gamma band activity in the auditory cortex after overcompensation in comparison to baseline measurements. This was, however, not the case for the control or the compensation groups. In conclusion, music therapy compensating for hearing loss is not beneficial in suppressing tinnitus, and overcompensating hearing loss actually worsens tinnitus, both clinically and electrophysiologically.

2012 Published by Elsevier B.V, in Hearing Research, Hear Res. 2012 Oct 23. pii: S0378-5955(12)00244-4. doi: 10.1016/j.heares.2012.10.003. Authors: Vanneste Svan Dongen MDe Vree BHiseni Svan der Velden EStrydis CKathleen JNorena ASerdijn WDe Ridder D

Neurostimulation causes nerves cells to grow back and allows paralyzed to walk again

Article from De Volkskrant, dd. Oct. 27, 2012, entitled "Paralyzed walks again"

Article from De Volkskrant, dd. Oct. 27, 2012, entitled “Paralyzed walks again”

Eddy was damn right when after the disk in his spinal cord was removed by the neurosurgeon and he lost almost all the feeling in one of his legs due to the acute hernia. By means of transcutaneous stimulation of his foot and leg he was able to regain feeling and control over his muscles  and walk again. The method was not proven scientifically yet, but obviously worked, as we witnessed from closeby. Now the scientific proof is there.

Exciting times ahead, if you ask me.

Wouter

Article in “De Telegraaf”, September 29, 2012 (in Dutch)

Artikel Telegraaf

Wouter

We have migrated!

Dear readers of and contributors to the Biomedical Electronics weblog: we have now migrated to WordPress. This rather smooth handover has been completed yesterday and has resulted in a new look, but most importantly, a better user interface. Please try it out for yourself! I look forward to seeing your fine contributions coming in. Also if you have suggestions for the look and feel of the weblog, please do not hesitate to contact me.

As a noteworthy fact, this month one of our contributions reached 10,000+ views.

Best regards,

Wouter

First implantation of a vestibular implant

Today it was reported in ‘De Volkskrant’ that doctors of Maastricht University Medical Center have succeeded in, for the first time ever, implanting an artificial balance organ, a vestibular implant, in two patients. A vestibular implant is more or less a cochlear implant that relays information on orientation and accelleration onto the hair cells in the vestibula, the small organ attached to the cochlea that assists in preserving balance. According to Prof. Robert Stokroos of UMCM, the first measurements after the surgery showed positive results. Very important, as far as I understand, will be whether the vestibular implant will allow for perfect integration of the balance information delivered by the implant and the balance perceived by the eyes.

Despite all this, I believe we have exciting times ahead for the application of novel neurostimulating devices.

Wouter

Motivation 2.0

Today, it was announced in the news that the Netherlands is again facing, now for the third time, a case of severe fraud in science. A professor in Consumer Behavior at the Erasmus University Rotterdam has resigned from his duties and two of his articles will be withdrawn from the journals they were published in.

Mark my words. We’re not dealing with intrinsically bad people here and before you raise your fingers at the scapegoats, read this [taken from the Book ‘Drive’ by Daniel H. Pink]: "Goals may cause systematic problems for organizations due to narrowed focus, unethical behavior, increased risk taking, decreased cooperation and decreased intrinsic motivation. Use care when applying goals in your organization."

It makes me wonder to what extent the universities are falling into the pits they digged themselves.

Wouter

Mission Possible

In order to present the Biomedical Electronics Group of Delft University of Technology to a couple of companies, it made sense to reveal our mission statement. So here it goes…

The mission of the Biomedical Electronics Group of Delft University of Technology is "to provide the technology for the successful monitoring, diagnosis and treatment of cortical, neural, cardiac and muscular disorders by means of electricity." In order to reach this goal we investigate and design circuits and systems for electrical stimulation, ExG readout, signal specific analog signal processing, power management/conversion, energy harvesting and wireless communication, to be applied in future wearable and implantable medical devices, such as hearing instruments, cardiac pacemakers, cochlear implants and neurostimulators.

So how about that? Reactions are welcome via this blog.

Wouter

Excuse me, I am just a university professor

LoserThe
economic downturn in Europe, often denoted as the Euro crisis, is often rightly associated with the negative effects of the "neoliberal meritocracy" we
live in. The term meritocracy perhaps deserves some explanation. It was
coined in the book of Michael Young, entitled "The rise of the
Meritocracy", which appeared in 1958 and sketches a world in which the
best, i.e., those with the highest intelligence and the highest work
power, climb the social-economical ladder very fast, and vice versa [1].

Also the universities, and Delft University of Technology
unfortunately is no exception, suffer under the yoke of this neoliberal
meritocracy, which has created an atmosphere in which professors only
become visible and respected if they have successfully competed with their colleagues
and have won an award, of which they subsequently advocate that it is
the most prestigious in their field.

Another effect of this
neoliberal meritocracy is that it all is about numbers that pretend to
reflect quality rather than that they are part of the quality itself. To me, the
best book ever on true quality is Robert Pirsig’s "Lila",
the worthy successor of "Zen and the Art of Motorcycle Maintenance" (1974) and
which appeared in 1991. Naturally, an abstract topic like "quality" that
needs more than a book to give the reader a notion of its true essence
cannot be reduced to a number. Yet, in universities, the meritocracy
florishes due to numbers. In a self-assessment, made for the periodical
accreditation of our university, the quality of the research of its
professors was reduced to a number, in this case the Hirsh index or h-index. For a detailed discussion on h-index I refer you to the many web sites of Elsevier’s Scopus,
but for the moment just remember that it is a number that supposedly
indicates the influence of one’s scientific publications and thereby of the author himself on the field.
As if all fields are equally important, of equal size and all scientific communities
deal with their publications, authors, etc. in the same manner. Of
course not!

Quality of education of course is another aspect that
should be of concern to universities. Unfortunately, here the numbers
are more difficult to generate, if possible at all. As also education is more
inside-oriented and research is more outside-oriented and universities
would like to show to the outside world how great they are, they have a
tendency to stress the impact of their research more than the impact of
their education. Also, a university is an education institute of which
the major outcome, i.e., the student that successfully completes his studies
with a diploma on time and thereby is well equipped for his professional life to come, is a result of the great work of many individuals in a
team, including, of course, the student himself, but definitely more
difficult to trace back to the individual effort of a single professor. I
believe that, as a consequence of this more hidden impact of the
efforts of an individual professor, less appreciation exists among their
colleagues and bosses for the great work they are doing. Also, it is
striking to notice how many years must pass before a teacher that
clearly underperforms (according to which numbers?) will be no longer
able to pursue his damage. 

However, this is also not my main
issue here. I guess my main issue is that in this meritocratic
university system there is no appreciation and thus no room for the glue
that keeps things together. To give you a few examples:

  1. If a
    professor falls ill and a colleague takes over and brings the expedition
    to a satisfying close, this will most often go unnoticed as the project
    or course officially is still under the wings of the original professor. You have to be
    a loser to help your colleague in situations like these. 
  2. If a
    student suffers from a delay in his studies due to lack of motivation,
    skills or talents and he finally makes it due to the strong motivation
    and commitment offered by his thesis advisor, whereas the thesis advisor
    could 
    instead  have spent his time on supervising at least two other more
    brilliant students, according to the numbers, the advisor did the wrong
    thing. You must be a loser to spend your time on less brilliant
    students.
  3. If a thesis advisor trains a student to let the creativity and the innovation come from the student himself rather than that he imposes his own solution to a
    scientific or engineering problem on a student,
    the result takes longer time to come to fruition and therefore requires
    more time from the thesis advisor. You must be a loser if you don’t tell
    your students exactly what to do and how. 
  4. If a thesis
    advisor himself writes major parts of the scientific paper that is based
    on the work of a student, this paper has more chance to be accepted for
    publication and even win an award. You must be a loser to let your
    student write his own paper.

If situations like those sketched above arise, I have accepted and even deliberately decided to be the loser. 

Wouter

[1] Paul Verhaeghe: De effecten van een neoliberale meritocratie op identiteit en interpersoonlijke verhoudingen, Oikos 56, 1/2011

Award for Senad Hiseni

On March 16, Ir. Senad Hiseni received an award from the Biomecial
Electronics Foundation
for excellence in research on implantable
medical devices with a high scientific, engineering, clinical and
societal relevance.
 
Congrats, Senad!
 

Dance4Life, Oranjetrophy and the Biomedical Electronics Foundation

The Biomedical Electronics Foundation supports the Orange Trophy in its action for Dance4Life and Miep and Christy of Team DrivingCrazy
in particular. On May 3, 2012, Miep (at left) received the donation
from Wouter (at right) and fixed two stickers of the Biomedical
Electronics Foundation on both sides of the car.