Category Archives: General

Injectable Electronics: dawn of a new era in electroceuticals?

Injectable electronics still need to become smaller

Frequent readers of this weblog may still remember a previous post, entitled “And the paralyzed will walk again“. This phrase comes from a Discovery Channel movie/documentary, called “2057: the body”, in which it is predicted that by the year 2057 you will be able to survive a three story fall and even be able to walk again as there will be tiny microstimulators attached to your muscles, which can be injected.

Injectable electronics, how fascinating would that be! No more lengthy surgeries, during which only a single, bulky device is implanted, but rather a procedure that takes less than a couple of minutes, during which multiple micro-stimulators are inserted via a seringe. Once done, these stimulators will form a wireless network and will provide the motory neural pathway with well-timed electric stimuli necessary to evoke the correct contraction of the multiple muscles involved in a delicate movement or even seemingly simple posture control.

But how feasible is this idea of injectable electronics? If you search for the term injectable electronics, you will most likely find a lot of references to the work of John Rogers, professor at the University of Illinois in the US, who built “an electronic LED device so tiny it can be injected into delicate tissue, such as in the brain, without harming it“.
Other links that can be found refer to work done on silk implants or even magnesium implants that are either stretchable or can easily dissolve into the body once the good work has been done.

I personally believe that we only can create injectable electronic devices if they have at least some intelligence in them. For this, the good old silicon would be an excellent candidate. Silicon is a nice and friendly biocompatible material, can be made bendable (by thinning the substrate) or stretchable (by removing the substrate altogether at some points). And what’s more, silicon can accommodate stimulation circuitry, sensors, signal processing, communication electronics, antennas, battery foils, all the good stuff needed to make a good injectable.

Of course, in order not to damage the tissue that the electronic device is injected in, it needs to be small, i.e., thin and narrow. It is however allowed to make it long, e.g., a couple of millimeters up to one or two centimeters. These unconventional dimensions raise very exciting technological challenges, such as:

  • how can we create electronic integrated circuits (ICs) that are merely one-dimensional, i.e., are not wider than one, maximally two, bondpads?
  • how can we transfer information and energy to an implant that has virtually no area?
  • what kind of material should we use for the antenna and electrodes?
  • will a Li-Ion battery foil have enough capacity to provide successful stimulation of the tissue, or should we refrain from using batteries altogether?

There obviously is still a lot to do. Exciting stimes ahead, if you ask me.

Wouter

6152 chapter downloads for Circuits and Systems for Future Generations of Wireless Communications

Since its online publication on Jun 02, 2009, there has been a total of 6152 chapter downloads for your book on SpringerLink, our online platform. Over the last year(s) the download figures have been as follows:

Year Chapter Downloads
2012 806
2011 1042
2010 2852

This means your book was one of the top 50% most downloaded eBooks in the relevant Springer eBook Collection in 2012.
To further widen the distribution of your book, it has also been made available as an Amazon Kindle eBook version.

First dutch blind patient can see again

Today, the dutch newspaper Trouw published an article in which it reports about the first blind dutch patient being able to see again. This is made possible by a retinal implant developed by the company Second Sight, which saw its implant called Argus II being approved by the FDA this spring. As with most types of implants, it is only able to restore the original functioning of the biological senses with a limited resolution, urging a further improvement of the implant. Nonetheless, this is a huge step forward in improving the quality of life of people suffering from a reduced or even complete failure of their biological senses.

A new name, but Biomedical Electronic remains

Biomedical Electronics Lab

Dear Reader,

The Biomedical Electronics Group underwent a small name change. From now onwards, the group is called “The Biomedical Electronics Laboratory”.

Its mission is “to provide the technology for the successful monitoring, diagnosis and treatment of cortical, neural, cardiac and muscular disorders by means of electroceuticals.”

To this end it conducts research on, provides education in and helps creating new businesses in neuroprosthetics, biosignal conditioning / detection, transcutaneous wireless communication, power management, energy harvesting and bioinspired circuits and systems.

Mark Stoopman’s work in the press

Long-range RF energy harvester with record sensitivity to power small sensor systems

Long-range RF energy harvester with record sensitivity to power small sensor systems

Today a press release appeared featuring the work of Mark Stoopman in collaboration with the Holst Centre and TU/e, entitled “Long-range RF energy harvester with record sensitivity to power small sensor systems”.

If you are interested in the whole press release, including some juicy pictures, please visit http://imec.fb.email.addemar.com/c2108/e0/h13206/t2/s0/index.html.

Enjoy!

Wouter

Aside

At the annual general assembly of the Delft Research Center on ICT (DIRECT), we proudly presented one of TU Delft’s faculty flagship projects “Beethoven”. Beethoven is a technology-driven research project on electroceuticals that aims at the design of a flexible brain … Continue reading

New Book: EMI-Resilient Amplifier Circuits

EMI-Resilient Amplifier Circuits

EMI-Resilient Amplifier Circuits

van der Horst, Marcel J., Serdijn, Wouter A., Linnenbank, André C.

2013, XIV, 300 p. 75 illus., 1 illus. in color.

ABOUT THIS BOOK
Describes design methods that incorporate electromagnetic interference (EMI) in the design of application specific negative-feedback amplifiers
Provides designers with a structured methodology to avoid the use of trial and error in meeting signal-to-error ratio (SER) requirements
Equips designers to increase EMI immunity of the amplifier itself, thus avoiding filtering at the input, reducing the number of components and avoiding detrimental effects on noise and stability
This book enables circuit designers to reduce the errors introduced by the fundamental limitations and electromagnetic interference (EMI) in negative-feedback amplifiers. The authors describe a systematic design approach for application specific negative-feedback amplifiers, with specified signal-to-error ratio (SER). This approach enables designers to calculate noise, bandwidth, EMI, and the required bias parameters of the transistors used in application specific amplifiers in order to meet the SER requirements.

· Describes design methods that incorporate electromagnetic interference (EMI) in the design of application specific negative-feedback amplifiers;

· Provides designers with a structured methodology to avoid the use of trial and error in meeting signal-to-error ratio (SER) requirements;

· Equips designers to increase EMI immunity of the amplifier itself, thus avoiding filtering at the input, reducing the number of components and avoiding detrimental effects on noise and stability.

Content Level » Research

Keywords » Analog Integrated Circuit Design – EMI – EMI-resilient – Electromagnetic Compatibility – Electromagnetic Compatibility Engineering – Electromagnetic Interference – Electromagnetic Interference-resilient – Negative-feedback Amplifier Circuits – Signal-to-Error Ratio

Related subjects » Applied & Technical Physics – Circuits & Systems – Electronics & Electrical Engineering

TABLE OF CONTENTS
Introduction.- Decreasing the disturbance coupled to amplifiers.- Modelling of active devices.- The Cascode and Differential amplifier stages.- Design of EMI-resilient single-stage amplifiers.- Design of EMI-resilient dual-stage amplifiers.- Realizations.- Conclusions and recommendations.

Quote from Michael Merzenich

While reading, correcting and enjoying the essay of Jose Manuel Rosas Escobar, I stumbled on a quote from Michael Merzenich, which I think you should read and comtemplate on.
So here goes…
“The success with any complicated prosthetic device relates as much to how the brain adjusts to it, accepts it and controls its use as it does to the device itself. If we can figure out how to engage the brain to do its part, it can make a merely adequate neural prosthetic device work marvelously.”

Wouter

New Biomedical Electronics Group photo

Biomedical Electronics Group anno 2013

Biomedical Electronics Group anno 2013

Today we made a new group picture. And thus we proudly present:

The Biomedical Electronics group anno 2013. From left to right:
Wu Chi Wing, Yao Liu, Duan Zhao, Menno Vastenholt, Sophinese Iskander-Rizk, Cees-Jeroen Bes, Alexandra-Maria Tautan, Lucho Gutierrez, Wouter Serdijn, Horacio Jimenez, Marijn van Dongen, Matthijs Weskin, Senad Hiseni, Joeri Willemse, Mark Stoopman, Yongjia Li, Andre Mansano, Wannaya Ngamkham.

Not on the photo: Sumit Bagga, Robin van Eijk, Marcel van der Horst, Marion de Vlieger, Chutham Sawigun, Sander Fondse, Joeri Biesbroek

Picture taken March 6, 2013.

Marijn received best presentation award at BME 2013 Conference

The Biomedical group this year attended  the BME 2013 (the 4th Dutch Bio-Medical Engineering Conference 2013) conference, held at 24th and 25th of January 2013. Our group held 5 oral presentations (Senad, Yao, Wannaya, Wu, Marijn) and 2 poster presentations (Rico and me). Marijn was selected as one of the four nominees for the best oral presentation award. Moreover, he was not only nominated, he also won this award! Congratulations, Marijn! 🙂