Cochlear Implants: A message from patients to researchers

From the information below I feel that as researchers we need to develop cochlear implants (CIs) further. This I consider my duty!!

cochlear Ltd.From "Events and Research in Speech, Language, and Hearing Disorders":

CI user’s mom said "I have a baby with CI and I wish researchers can find a very reliable way to do totally implanted CI, because I think people need hearing always and in each condition."

"I feel that we are placing to much hope into the development of a completely internal implant being released in our lifetime. I have a son who has bilateral implants and it would be amazing if he could swim, bathe, sleep and have sound during these activities. But the fact that he can have sound all of the other time is a modern-day miracle and we are so thankfull to all people putting in endless hours of research!"

"I’ve been fitted with a cochlear implant for about a year and still can’t really enjoy music. Will a new fully implantable one improve the sound quality and enable people to hear music?"

Cochlear Implant Swimming Youtube Video, Click here:

CI user’s mom said "Thanks for this video. Since I watched this video, I have taken my daughter swimming a lot more and she enjoys it way more than before. Before we would spend about 5-10 minutes in the pool. Now she wants to spend all day."

Wannaya/.

Brain vs. Computer

The brain is an amazing thing. That mysterious little jelly pudding up there in your head has an unsurpassed computing power that we all use everyday to at least some extent. Humans have always been amazed by the brain and there has been a strong trend throughout history to build machines which can take over some of that computing power.

From the first electronic computer Colossus (using 1500 vacuum tubes and used to crack the Enigma code during World War II) until recently the IBM Watson: a computer which is able to understand natural questions, which can perform reasoning based on a huge amount of information stored in its memory and can come up with the correct answer. And all that within 3 seconds.

Watson consists of 90 IBM Power 750 servers, 15 Terabytes of RAM, 2880 processor cores and can operate at 80 teraflops. Very impressive specifications. A couple of days ago Watson competed in a Jeopardy! game against two humans and he managed to win quite impressively (although he made one quite shameful mistake).

Watson competing against humans

So does that mean that a bunch (ok, quite a big bunch) of processors can immitate the human brain? Well, to some degree it has proven it can. But the brain can do a lot more than understanding and answering questions. And besides functionality there is another factor, just like Dr. Bernard S. Meyerson, IBM’s vice president for innovation, mentioned: "The fact is that a human being is impossible to beat right now, in the sense of power efficiency, because you’ve got this little 20-watt thing, the brain, going up against many kilowatts."

So does this fact mean all the efforts made by the researchers are in vain? Definitely not, of course. It just means that we will have to keep using our little 20 watt miracle in order to come up with even smarter machines!

 Marijn van Dongen

Cell phones affect the glucose concentration in the brain close to the antenna

The Journal of the American Medical Association will soon publish an article on the effects of the use of a cell phone on the glucose concentration in the region of the brain close to the antenna. According to the Preliminary Communication published today, the brain cells exposed to 50 minutes of radiation from the cell phone had a significant increase in their glucose metabolism of about 7 percent. Its clinical significance, however, is yet unknown.

Though I understand the clinical study conducted and the scientific method applied, there are some comments that I would like to vent.

The first one is about the state of the mobile phones used. The article mentions that they were on for 50 minutes. But what does "on" mean exactly? Were they just on standby, waiting for a call? Was a call being made? If so, for how long? Was there any data passed between the cell phone and its base station? But the total "talk time", or better, transmission time, is not revealed in the article.

Moreover, its is known that the amount of power transmitted by the cell phone depends on the distance to the base station. Fortunately, the cell phone decreases its output power when channel conditions are good enough, thereby extending its talk time and reducing co-channel interference. This thus implies that the amount of radiated power is another unknown in this study.

Finally, and this becomes evident from a literature study and experiments conducted by our own Mark Stoopman, the amount of energy being absorbed by brain tissue strongly depends on the frequency being used. This, in turn, depends on the type of service (GSM, UMTS, etc.) and the provider being used. GSM 1800, for instance, in use by, e.g., T-Mobile, leads to more tissue absorption than GSM 900.

All-in-all, a lot of unknows, if you ask me.

Wouter

Would you allow your brain to drive your car?

German scientists have managed to develop a car that can be controlled by signals recorded from the brain. These signals are captured by a brain interface based on electro-encephalography (EEG) sensors, which was originally designed for gaming.

  

Click here for a video that highlights the thought-powered driving system on a trip to the airport. More information on the BrainDriver can be found here.

Currently, the system still experiences serious latency, as the brain waves first have to be analyzed, clustered and classified — I’d recommend a multi-wavelet transform for doing so — before appropriate action can be taken. It still will take a while before we really can take our hands off the wheel, sit back and imagine we’re at our destination already.

Micropower scavenged UWB radios

The windmill is a beautiful artifact and very recognizable in the Dutch landscape. It converts wind energy into rotational motion, and is one of the earliest energy harvesters in history. Today, research on energy harvesting is not only focussing on generating megawatts of electrical power, but also deals with micropower harvesters that can for example be used to power small wireless sensors or RFID tags.

Micopower energy harvesters can convert energy from the environment (vibrations, thermal difference, solar, RF) into electrical energy that can be stored in a capacitor or battery.

This allows wireless sensors to transmit their payload once the harvester has collected enough energy. Thus, in principle, the wireless sensor can have an infinite lifetime. Of course, the amount of energy that can be harvested depends on the application. One of the reasons why micropower scavenged wireless sensors are not yet widely used today is that current radio solutions such as ZigBee or Bluetooth consume (much) more power than the harvester can deliver.

A promising solution for this problem is to use Ultra-WideBand communication. UWB radio makes use of carrierless, short duration pulses to transfer the information. Since the radio can be switched off during the time laps between two pulses, the average power consumption can be low enough so that it can be combined with an energy harvester. That’s why in this group we are working on energy scavenged UWB radios since they seem to be the perfect match. Another distinct advantage is that UWB communication can offer accurate localization within a few cm’s. This means that finding your missing car, laptop or wife will be a piece of cake without ever having to change the radio battery!

Mark Stoopman

Current between the ears…

 "Current between the ears" 

In the weekend edition of a major Dutch newspaper (called the Volkskrant), the science section immediately got my attention. "Current between the ears". Since most people seem to have a brain between their ears, this article might be telling us about neural stimulation.

And so it did! It describes a technique called ‘Transcranial Direct Current Stimulation’ (tDCS). Two external electrodes are placed on the head of the subject. By sending a DC current in the order of 1mA through these electrodes the brain functionality can be influenced.

At the positive electrode, the tissue potential is slightly elevated. This means that the threshold for neurons to become activated is decreased and therefore the part of the brain close to the positive electrode becomes more active. The opposite holds for the negative electrode: this part becomes less active.

In this way it is possible to either stimulate or suppress particular neural functions. It can for example be used to temporarily increase the memory ability of the brain. Or to suppress mechanisms that lead to addiction. Or to help depression patients by suppressing the part that is associated with bad feelings.

The big advantage of this technology is obviously that is is non-invasive. That must however also be a disadvantage. To support 1mA currents, the electrode must be quite big in order not to exceed their charge injection limitations. This means that the spatial resolution of this method must be quite poor: a relatively large area is affected using this method. 

Nevertheless the article shows some interesting results, both obtained by the department of Developmental Psychology of the UvA and by research groups throughout the world. Once again it shows the fascinating world that opens up as soon as we apply (electrical) technology to the most complex organ we have: our brain.

Marijn van Dongen 

Are we all cyborgs now?

Check it out for yourself at TED.com, in this inspiring talk by Amber Case. Keep an eye on your self, though.

TED logo

Another one, highly recommended, is by Oliver Sacks, the famous neurologist and author (e.g., of the book Musicophilia). In this presentation, he points out an interesting link between visual hallucinations and tinnitus. Click here.

Can the upcoming solar storm turn your pacemaker into a killer inside you?

It has been predicted that today (Febr. 17, 2011) one of the largest solar storms in years will reach the earth and may interfere with sensitive electronic equipment, such as GPS receivers in cars and PDAs. Also air traffic and power grids may suffer from this kind of interference.

 Solar Storm 

Solar storms, also called geomagnetic storms, are caused by solar coronal mass ejections and modify the electromagnetic fields in the ionosphere, magnetosphere and heliosphere. They usually last only one or two days and can cause auroras further away from the poles than usually. According to Wikipedia, "On March 13, 1989 a severe geomagnetic storm caused the collapse of the Hydro-Québec power grid in a matter of seconds as equipment protection relays tripped in a cascading sequence of events. Six million people were left without power for nine hours, with significant economic loss."

So how dangerous are these solar storms for life-supporting devices like pacemakers and neurostimulators? In order to answer this question, we need to understand the physical and electrical effects of solar storms. Solar storms induce fluctuations in the Earth’s magnetic field. These fluctuations, in turn, can induce currents in large electrically conducting structures, such as power grids and metal pipelines, leading to damaged transformers and corrosion. Solar storms also influence the electrical currents in the magnetosphere and the ionosphere and thereby affect wireless communication that propagates through them.

So my conclusion: as long as you do not use your shortwave radio or CB set to control your implantable device remotely and you do not power it from the mains, you’re safe. Ain’t that a relief?

Wouter

Ice skating and guitar solos

I’m writing this little contribution on Saturday night. Most people must be either watching the World Championships Ice Skating or enjoying themselves in the nightlife. Maybe you are lucky and you are in the Oosterpoort (Groningen) tonight listening to a concert by ‘Gare du Nord‘. Or you prefer to immerse yourself in the sounds of fabulous guitar solos and keep dancing like there’s no tomorrow. 

But there will be a tomorrow. And the more successful last night was, the harder the Sunday morning is. With a liver getting in overdrive and a brain complaining about a lack of water, you wonder why you cannot sleep any further. Soon you realize it must be that annoying beep in your head. Maybe standing next to the big loudspeakers was not a good idea after all. Well, let’s first take a shower, the beep will be gone during the course of this lazy Sunday.

 woman suffering from tinnitus 

Or not… Imagine this beep will stay with you. Always. More than a million people in Holland suffer from a disease called Tinittus. In about 10% of the cases the beep (or noise) is so loud that it limits them in their daily life. No effective treatment exists until today. But we are working on it. Brain stimulation can be an effective treatment method. And in our group we are developing the ‘uStim’-stimulator: it can stimulate the brain in a unique manner so that we can stop the beep. We use technology to manipulate faulty activity in the brain.

Sounds interesting? Keep reading this blog for updates about this little device. Oh, and keep enjoying yourselves on (Saturday) nights. But just as with all things in life: keep it safe. Unless you are watching the World Championships Ice Skating. I cannot think of any way how you can harm yourself while doing that…

Marijn van Dongen 

Electric stimulation turns geek into sex god

"Electrical stimulation of certain hypothalamic regions in cats and rodents can elicit attack behaviour," is what we can read in Nature today. But also "Neurons activated during attack are inhibited during mating, suggesting a potential neural substrate for competition between these opponent social behaviours." If the same holds for human beings, which is highly probable, then we are not far away from the situation in which we can replace Cialis by a healthy dosis of instant neurostimulation or switch the neurostimulator to Arousal Mode No. 2 to beat the guy that left the bar with another one’s girlfriend. As long as they do not take my Erdinger, I’m fine.

Jokes aside, it is known that both regions in the brain are closely located to one another, together with the part that controls voluntary urination. So my advice: don’t try this at home.